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Genic and intergenic locations Topography Investigation could not be performed for genic and intergenic location asymmetry as the quantity of mutations fulfilling our constraints was insufficient or this signature wasn't nevertheless analysed.

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In Fig. 5, the APC mutations in samples from polyps also match the pks+ signature. In polyp G, we detected a T to C mutations in ATT context on APC gene As well as in polyp F, There's a brief T-del in T-homopolymer. It indicates that pks+ may be a applicant process chargeable for mutations in cancer driver genes slot gacor gampang menang With this most cancers client.

The y-axis is definitely the reads counts from E.coli. The red/gray shade from the bars denotes the existence/absence of clb genes because the clb genes represent pks genomic island and encoding colibactin.

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